AUSTIN, Texas — Best-selling author and columnist Molly Ivins, the sharp-witted liberal who skewered the political establishment and referred to President Bush as “Shrub,” died Wednesday after a long battle with breast cancer. She was 62.

Ivins died at her home while in hospice care, said David Pasztor, managing editor of the Texas Observer, where Ivins had once been co-editor.

Ivins made a living poking fun at politicians, whether they were in her home state of Texas or the White House. She revealed in early 2006 that she was being treated for breast cancer for the third time.

More than 400 newspapers subscribed to her nationally syndicated column, which combined strong liberal views and populist humor. Ivins’ illness did not seem to hurt her ability to deliver biting one-liners.

“I’m sorry to say (cancer) can kill you, but it doesn’t make you a better person,” she said in an interview with the San Antonio Express-News in September, the same month cancer claimed her friend former Gov. Ann Richards.

To Ivins, “liberal” wasn’t an insult term. “Even I felt sorry for Richard Nixon when he left; there’s nothing you can do about being born liberal — fish gotta swim and hearts gotta bleed,” she wrote in a column included in her 1998 collection, “You Got to Dance With Them What Brung You.”

In a column in mid-January, Ivins urged readers to stand up against Bush’s plan to send more troops to Iraq.

“We are the people who run this country. We are the deciders. And every single day, every single one of us needs to step outside and take some action to help stop this war,” Ivins wrote in the Jan. 11 column. “We need people in the streets, banging pots and pans and demanding, ‘Stop it, now!”’

Ivins’ best-selling books included those she co-authored with Lou Dubose about Bush. One was titled “Shrub: The Short but Happy Political Life of George W. Bush” and another was “BUSHWHACKED: Life in George W. Bush’s America.”

Dubose, who has been working on a third book with Ivins, said even last week in the hospital, Ivins wanted to talk about the project.

“She was married to her profession. She lived for the story,” he said.

Ivins’ jolting satire was directed at people in positions of power.

“The trouble with blaming powerless people is that although it’s not nearly as scary as blaming the powerful, it does miss the point,” she wrote in a 1997 column. “Poor people do not shut down factories. ... Poor people didn’t decide to use ‘contract employees’ because they cost less and don’t get any benefits.”

In an Austin speech last year, former President Clinton described Ivins as someone who was “good when she praised me and who was painfully good when she criticized me.”

Ivins loved to write about politics and called the Texas Legislature the best free entertainment in Austin.

“Naturally, when it comes to voting, we in Texas are accustomed to discerning that fine hair’s-breadth worth of difference that makes one hopeless dipstick slightly less awful than the other. But it does raise the question: Why bother?” she wrote in a 2002 column.

Texas Gov. Rick Perry, whom Ivins had playfully called “Governor Goodhair,” praised Ivins for her wit and insight. “Molly Ivins’ clever and colorful perspectives on people and politics gained her national acclaim and admiration that crossed party lines,” Perry said in a statement.